ProLiFiler Cancer Cell Panel Screening

The one stop solution for both 2D and 3D efficacy and potency testing

ProLiFiler is our recurring screening service, designed to test the therapeutic efficacy and potency of test compounds on a panel of well-characterized cancer cell lines.

Choose between 2D format for early-stage investigation into your compound efficacy or 3D spheroid format for advanced understanding of your compound potency in a more physiological setting.

Why work with Reaction Biology

• Ready when you are: our screens are performed regularly
• Mode of action studies comparing your test article IC₅₀ to hundreds of reference compounds
• Rapid turnaround time with results in just 5 to 6 weeks
• Confidence in the reproducibility of your data due to our semi-automated processes
• Flexible testing options: single drug or combination testing
• Validate your findings from 2D screens in a more physiologically relevant 3D spheroid format without changing service provider
• Option for in-depth bioinformatics analysis
  
  

2D Cancer Cell Panel Screening Services

Unlock Insights for Targeted Therapies

Are you in search of comprehensive insights into the efficacy of your anti-cancer compounds? Our ProLiFiler Cancer Cell Panel Screening includes 160 human cancer cell lines spanning 15 tumor types to deliver actionable data and guide your drug development journey

What Can I Learn?

• Identify sensitive tumor cell lines
• Understand susceptibility across cancer types
• Uncover genomic signatures for predictive drug responses
• Validate your drug's mode of action by comparing with control marketed drugs

Ready for a New Dimension?

Discover 3D ProLiFiler Spheroid Cancer Cell Panel Screening Service

Revolutionizing Drug Development with 3D Insights

Take your research to the next dimension with our 3D ProLiFiler Spheroid Cancer Cell Panel Screening service. Designed to assess therapeutic potency and tumor-penetrating efficacy, this service utilizes 3D spheroids grown from a diverse panel of 40 cell lines across 13 tumor types.

Advantages of 3D ProLiFiler:

• Evaluate drug responses across 40 3D spheroid cell lines
• Gain insights into your compound effectiveness and prioritize lead candidates before moving to more complex in vivo studies
• Preserve relevant signaling cascades, pH, oxygenation and nutrient gradients
• Reflect the tumor microenvironment through 3D cell-cell and cell-ECM interactions

At Reaction Biology, we empower your drug development journey by providing advanced screening services tailored to your research needs. Choose ProLiFiler for in-depth insights and a decisive edge in developing targeted therapies. Contact us to initiate a transformative collaboration.