AACR Annual Meeting 2025

April 25 - 30, 2025   •   Chicago, IL   •   Booth #1242

AACR2025-landingpage3

The Reaction Biology team is attending AACR 2025 in Chicago!  Connect with our experts in person at Booth #1242 to explore our discovery and development services and learn why Reaction Biology has been the industry leader in supporting discovery innovation for over 20 years.

Book a Meeting

Learn about our broad end-to-end oncology platform, with products and services from proteins to in vivo, including:

  • Our diverse range of over 2,000 target-specific biochemical assays, including HotSpot™, the industry leading kinase activity assay 

  • A wide variety of cell-based assays, including our large collection of target engagement assays, and ProLiFiler™, our 2D/3D cancer cell panel screening service

  • A range of biophysical assays, including Surface Plasmon Resonance (SPR)

  • A unique portfolio of in vivo pharmacology services, including xenograft, metastatic, bone lytic, hollow fiber, and our novel SubQperior™ subcutaneous models

  • Our in vitro and in vivo immuno-oncology platform, with global flow capabilities including spectral flow cytometry

  • InVEST™: our in vitro biochemical, functional, and cardiac safety screening service, including InVEST44, the industry standard panel for early identification of off-target interactions

At Reaction Biology, we help our clients advance drug development, every day.  Visit us at AACR 2025 to learn how we can power your next breakthrough.


Poster Presentations

Visit one of our nine poster sessions to discover some of our new scientific developments.

Sunday April 27, 2025

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  • 02:00 PM - 05:00 PM
  • Poster section 21

#481 Development of a rapid method for the detection of neutralizing antibodies in sera of primates for viral gene therapy stratification

Gregor Sommerkamp, Eva M. Egenter, Katharina Schaich, Daniel Feger, Sebastian Dempe, and Jan E. Ehlert
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  • 02:00 PM - 05:00 PM
  • Poster section 2

#34 From fluid to function: leveraging ascites to build orthotopic ovarian cancer models

Cheryl Davis, Melissa Tran, Ben Hoerner, Victoria Caruso, Marcus Josey, Corrine Silvio, Shannan Wenzel, Shorena Nadaraia-Hoke, Chris Holding, Dawn Lusk

Monday, April 28, 2025

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  • 09:00 AM - 12:00 PM
  • Poster section 4

#1314 Enhanced Metastasis Modeling in Mice: Impact of Primary Tumor Removal and Optimized Injection Techniques on Therapeutic Assessment

Jonas Hummel, Philipp Metzger, Roland Sonntag, Dennis Borrero-Wolff, Gojko Bijelic, Cynthia Obodozie, and Holger Weber
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  • 02:00 PM - 05:00 PM
  • Poster section 15

#2891 In Vitro Comparison of Kadcyla and Enhertu in Breast Cancer with Varying HER2 Expression: Proliferation, Internalization, Bystander Effects and Toxicity

Veronica Bergo, Philipp Metzger, Valerie Oberhardt, Jan Ehlert, and Holger Weber
P
  • 02:00 PM - 05:00 PM
  • Poster section 19

#2997 Cell-based assay platforms for NLRP3 inflammasome drug discovery

Jianghong Wu, Li Liang, Peter Gallagher, Yong Wan, and Haiching Ma

Tuesday, April 29, 2025

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  • 09:00 AM - 12:00 PM
  • Poster section 20

#4363 Establishment of plasma inhibitory kinase assays (PIA) to detect functional drug levels in patient plasma

Lena Pilgermayer, Eva M. Egenter, Katharina Schaich, Daniel Feger, and Jan E. Ehlert
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  • 09:00 AM - 12:00 PM
  • Poster section 31

#4616 Detection of Phosphorylated Biomarkers in Clinical Blood Samples: A Flow Cytometry Platform Utilizing Smart Tube Fixation

Valerie Oberhardt, Philipp Metzger, Carla Castro, and Holger Weber

Wednesday, April 30, 2025

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  • 09:00 AM - 12:00 PM
  • Poster section 37

#7233 An In Vivo Co-Injection Model for Studying Macrophage Polarization and Therapeutic Repolarization in Tumor Development

Philipp Metzger, Valerie Oberhardt, Carla Castro, and Holger Weber
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  • 09:00 AM - 12:00 PM
  • Poster section 24

#6966 Apparent potency of small molecule inhibitors is influenced by the choice of substrate in LIMK biochemical in-vitro kinase activity assays.

Robert Torka, Andreas Gericke, Frank Totzke, Carolin Heidemann-Dinger, Constance Ketterer, Thomas Weber, Daniel Mueller